Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian Carcinoma

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from Italian OC patients...

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Autors principals: De Marco, Carmela, Rinaldo, Nicola, Bruni, Paola, Malzoni, Carmine, Zullo, Fulvio, Fabiani, Fernanda, Losito, Simona, Scrima, Marianna, Marino, Federica Zito, Franco, Renato, Quintiero, Alfina, Agosti, Valter, Viglietto, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567053/
https://ncbi.nlm.nih.gov/pubmed/23408974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055362
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