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Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin

BACKGROUND: Colon cancer stem cells may drive carcinogenesis and account for chemotherapeutic failure. Although many markers for these cells have been proposed, there is no complete agreement regarding them, nor has their presence in the early phases of carcinogenesis been characterized in depth. ME...

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Main Authors: Femia, Angelo Pietro, Dolara, Piero, Salvadori, Maddalena, Caderni, Giovanna
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566940/
https://ncbi.nlm.nih.gov/pubmed/23374535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-48
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