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Mucin Depleted Foci, Colonic Preneoplastic Lesions Lacking Muc2, Show Up-Regulation of Tlr2 but Not Bacterial Infiltration

Mucin depleted foci (MDF) are precancerous lesions of the colon in carcinogen-treated rodents and humans at high risk. Since MDF show signs of inflammation we hypothesized that the defective mucous production would expose them to the risk of being penetrated by intestinal bacteria, which can be sens...

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Detalhes bibliográficos
Main Authors: Femia, Angelo Pietro, Swidsinski, Alexander, Dolara, Piero, Salvadori, Maddalena, Amedei, Amedeo, Caderni, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252347/
https://ncbi.nlm.nih.gov/pubmed/22242189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029918
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