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High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates
BACKGROUND: The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consists of cells filled – almost exclusively – with aberrant mitochondria. In turn,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566933/ https://ncbi.nlm.nih.gov/pubmed/23267669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6614-5-24 |
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