A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white Europeans

PURPOSE: Corneal curvature is a key determinant of the refractive power of the eye. Variants in two genes, FKBP12-rapamycin complex-associated protein 1 (FRAP1) on chromosome 1p36.2 and platelet-derived growth factor receptor alpha (PDGFRA) on chromosome 4q12, have shown genome-wide significant asso...

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Bibliografiset tiedot
Päätekijät: Guggenheim, Jeremy A., McMahon, George, Kemp, John P., Akhtar, Saeed, St Pourcain, Beate, Northstone, Kate, Ring, Susan M., Evans, David M., Smith, George Davey, Timpson, Nicholas J., Williams, Cathy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Molecular Vision 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566893/
https://ncbi.nlm.nih.gov/pubmed/23401653
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