An inherited NBN mutation is associated with poor prognosis prostate cancer

BACKGROUND: To establish the contribution of eight founder alleles in three DNA damage repair genes (BRCA1, CHEK2 and NBS1) to prostate cancer in Poland, and to measure the impact of these variants on survival among patients. METHODS: Three thousand seven hundred fifty men with prostate cancer and 3...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Cybulski, C, Wokołorczyk, D, Kluźniak, W, Jakubowska, A, Górski, B, Gronwald, J, Huzarski, T, Kashyap, A, Byrski, T, Dębniak, T, Gołąb, A, Gliniewicz, B, Sikorski, A, Świtała, J, Borkowski, T, Borkowski, A, Antczak, A, Wojnar, Ł, Przybyła, J, Sosnowski, M, Małkiewicz, B, Zdrojowy, R, Sikorska-Radek, P, Matych, J, Wilkosz, J, Różański, W, Kiś, J, Bar, K, Bryniarski, P, Paradysz, A, Jersak, K, Niemirowicz, J, Słupski, P, Jarzemski, P, Skrzypczyk, M, Dobruch, J, Domagała, P, Narod, S A, Lubiński, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
Soggetti:
Genetics & Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566821/
https://ncbi.nlm.nih.gov/pubmed/23149842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.486
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi