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Efficient synthesis of phenylene-ethynylene rods and their use as rigid spacers in divalent inhibitors

The synthesis of phenylene-ethynylene rods and their use as rigid spacers is described. Alternation of a Sonogashira reaction and silyl group cleavage was used to obtain rigid spacers with even and odd numbers of phenylene units. Preliminary applications of these rods in divalent systems are shown....

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Detalhes bibliográficos
Main Authors: Pertici, Francesca, Varga, Norbert, van Duijn, Arnoud, Rey-Carrizo, Matias, Bernardi, Anna, Pieters, Roland J
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566787/
https://ncbi.nlm.nih.gov/pubmed/23400701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.25
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