Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia

Overexpression of the mammalian homolog of the unc-18 gene (munc18-1) has been described in the brain of subjects with schizophrenia. Munc18-1 protein is involved in membrane fusion processes, exocytosis and neurotransmitter release. A transgenic mouse strain that overexpresses the protein isoform m...

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Main Authors: Urigüen, L, Gil-Pisa, I, Munarriz-Cuezva, E, Berrocoso, E, Pascau, J, Soto-Montenegro, M L, Gutiérrez-Adán, A, Pintado, B, Madrigal, J L M, Castro, E, Sánchez-Blázquez, P, Ortega, J E, Guerrero, M J, Ferrer-Alcon, M, García-Sevilla, J A, Micó, J A, Desco, M, Leza, J C, Pazos, Á, Garzón, J, Meana, J J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566728/
https://ncbi.nlm.nih.gov/pubmed/23340504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.149
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