Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene–gene–environment interaction

Epistatic gene–gene interactions could contribute to the heritability of complex multigenic disorders, but few examples have been reported. Here, we focus on the role of aberrant dopaminergic signaling, involving the dopamine transporter DAT, a cocaine target, and the dopamine D2 receptor, which phy...

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Autori principali: Sullivan, D, Pinsonneault, J K, Papp, A C, Zhu, H, Lemeshow, S, Mash, D C, Sadee, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566726/
https://ncbi.nlm.nih.gov/pubmed/23340505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.146
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