Carboxypeptidase M augments kinin B1 receptor signaling by conformational crosstalk and enhances endothelial nitric oxide output

G protein-coupled receptors (GPCRs) are the largest class of membrane proteins that play key roles in transducing extracellular signals to intracellular proteins to generate cellular responses. The kinin GPCRs, named B1 (B1R) and B2 (B2R) are responsible for mediating the biological responses to kin...

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Hauptverfasser: Zhang, Xianming, Tan, Fulong, Brovkovych, Viktor, Zhang, Yongkang, Lowry, Jessica L., Skidgel, Randal A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566571/
https://ncbi.nlm.nih.gov/pubmed/23183746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0290
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