Impact of anti-orthopoxvirus neutralizing antibodies induced by a heterologous prime-boost HIV-1 vaccine on insert-specific immune responses

BACKGROUND: The impact of anti-vector immunity on the elicitation of insert-specific immune responses is important to understand in vaccine development. HVTN 055 was a 150 person phase I randomized, controlled HIV vaccine trial of recombinant modified vaccinia Ankara (rMVA) and fowlpox (rFPV) with m...

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Detalhes bibliográficos
Main Authors: Walsh, Stephen R., Seaman, Michael S., Grandpre, Lauren E., Charbonneau, Cherie, Yanosick, Katherine E., Metch, Barbara, Keefer, Michael C., Dolin, Raphael, Baden, Lindsey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566524/
https://ncbi.nlm.nih.gov/pubmed/23142302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.10.093
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