Correlated Spatio-Temporal Fluctuations in Chromatin Compaction States Characterize Stem Cells

Stem cells integrate signals from the microenvironment to generate lineage-specific gene expression programs upon differentiation. Undifferentiated cell nuclei are easily deformable, with an active transcriptome, whereas differentiated cells have stiffer nuclei and condensed chromatin. Chromatin org...

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Detalles Bibliográficos
Autores principales: Talwar, Shefali, Kumar, Abhishek, Rao, Madan, Menon, Gautam I., Shivashankar, G.V.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2013
Materias:
Cell Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566460/
https://ncbi.nlm.nih.gov/pubmed/23442906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.033
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