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Correlated Spatio-Temporal Fluctuations in Chromatin Compaction States Characterize Stem Cells
Stem cells integrate signals from the microenvironment to generate lineage-specific gene expression programs upon differentiation. Undifferentiated cell nuclei are easily deformable, with an active transcriptome, whereas differentiated cells have stiffer nuclei and condensed chromatin. Chromatin org...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566460/ https://ncbi.nlm.nih.gov/pubmed/23442906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.033 |
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