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Direct Observation of Protein Unfolded State Compaction in the Presence of Macromolecular Crowding
Proteins fold and function in cellular environments that are crowded with other macromolecules. As a consequence of excluded volume effects, compact folded states of proteins should be indirectly stabilized due to destabilization of extended unfolded conformations. Here, we assess the role of exclud...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566456/ https://ncbi.nlm.nih.gov/pubmed/23442920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.020 |
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