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Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling

Glucocorticoids are extremely effective anti-inflammatory therapies, but their clinical use is limited due to severe side effects, including osteoporosis, muscle wasting, fat redistribution, and skin thinning. Here we use heavy water labeling and mass spectrometry to measure fluxes through metabolic...

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Detalhes bibliográficos
Main Authors: Harris, Charles, Roohk, Donald J., Fitch, Mark, Boudignon, Benjamin M., Halloran, Bernard P., Hellerstein, Marc K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566431/
https://ncbi.nlm.nih.gov/pubmed/23211515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00154.2012
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