Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling

Glucocorticoids are extremely effective anti-inflammatory therapies, but their clinical use is limited due to severe side effects, including osteoporosis, muscle wasting, fat redistribution, and skin thinning. Here we use heavy water labeling and mass spectrometry to measure fluxes through metabolic...

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Bibliographic Details
Main Authors: Harris, Charles, Roohk, Donald J., Fitch, Mark, Boudignon, Benjamin M., Halloran, Bernard P., Hellerstein, Marc K.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566431/
https://ncbi.nlm.nih.gov/pubmed/23211515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00154.2012
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