Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer

BACKGROUND: Aberrant DNA hypermethylation has been implicated as a component of an epigenetic mechanism that silences genes in cancers. METHODS: We performed a genome-wide search to identify differentially methylated loci between 26 tumor and adjacent non-tumor paired tissues from same lung cancer p...

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Main Authors: Park, Jong Y., Kim, Donghwa, Yang, Mihi, Park, Hyun Y., Lee, Sang Haak, Rincon, Maria, Kreahling, Jenny, Plass, Christoph, Smiraglia, Dominic J., Tockman, Melvyn S., Kim, Seung Joon
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566332/
https://ncbi.nlm.nih.gov/pubmed/23273563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2012.11.019
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