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Multiplexed Protease Activity Assay for Low Volume Clinical Samples Using Droplet Based Microfluidics and Its Application to Endometriosis

As principal degrading enzymes of the extracellular matrix, metalloproteinases contribute to various pathologies and represent a family of promising drug targets and biomarker candidates. However, multiple proteases and endogenous inhibitors interact to govern metalloproteinase activity, often leadi...

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Detalhes bibliográficos
Main Authors: Chen, Chia-Hung, Miller, Miles A., Sarkar, Aniruddh, Beste, Michael T., Isaacson, Keith B., Lauffenburger, Douglas A., Griffith, Linda G., Han, Jongyoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566300/
https://ncbi.nlm.nih.gov/pubmed/23157326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307866z
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