Fish Oil Attenuates Omega-6 Polyunsaturated Fatty Acid-Induced Dysbiosis and Infectious Colitis but Impairs LPS Dephosphorylation Activity Causing Sepsis

Clinically, excessive ω-6 polyunsaturated fatty acid (PUFA) and inadequate ω-3 PUFA have been associated with enhanced risks for developing ulcerative colitis. In rodent models, ω-3 PUFAs have been shown to either attenuate or exacerbate colitis in different studies. We hypothesized that a high ω-6:...

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Bibliographic Details
Main Authors: Ghosh, Sanjoy, DeCoffe, Daniella, Brown, Kirsty, Rajendiran, Ethendhar, Estaki, Mehrbod, Dai, Chuanbin, Yip, Ashley, Gibson, Deanna L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566198/
https://ncbi.nlm.nih.gov/pubmed/23405155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055468
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