Short Term Exercise Induces PGC-1α, Ameliorates Inflammation and Increases Mitochondrial Membrane Proteins but Fails to Increase Respiratory Enzymes in Aging Diabetic Hearts

PGC-1α, a transcriptional coactivator, controls inflammation and mitochondrial gene expression in insulin-sensitive tissues following exercise intervention. However, attributing such effects to PGC-1α is counfounded by exercise-induced fluctuations in blood glucose, insulin or bodyweight in diabetic...

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Detalhes bibliográficos
Main Authors: Botta, Amy, Laher, Ismail, Beam, Julianne, DeCoffe, Daniella, Brown, Kirsty, Halder, Swagata, Devlin, Angela, Gibson, Deanna L., Ghosh, Sanjoy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731348/
https://ncbi.nlm.nih.gov/pubmed/23936397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070248
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