Cadmium Induces Apoptosis in Pancreatic β-Cells through a Mitochondria-Dependent Pathway: The Role of Oxidative Stress-Mediated c-Jun N-Terminal Kinase Activation

Cadmium (Cd), one of well-known highly toxic environmental and industrial pollutants, causes a number of adverse health effects and diseases in humans. The growing epidemiological studies have suggested a possible link between Cd exposure and diabetes mellitus (DM). However, the toxicological effect...

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Main Authors: Chang, Kai-Chih, Hsu, Ching-Cheng, Liu, Shing-Hwa, Su, Chin-Chuan, Yen, Cheng-Chieh, Lee, Ming-Jye, Chen, Kuo-Liang, Ho, Tsung-Jung, Hung, Dong-Zong, Wu, Chin-Ching, Lu, Tien-Hui, Su, Yi-Chang, Chen, Ya-Wen, Huang, Chun-Fa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566170/
https://ncbi.nlm.nih.gov/pubmed/23405080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054374
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