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Thermosensitive Block of the Sabin Strain of Poliovirus Type I

The thermosensitive defect of the Sabin LSc2ab strain of poliovirus type I was studied. Transfer of infected KB cells from 36 to 38.5 C resulted in 30% inhibition of viral RNA replication but in 90% inhibition of formation of virions. Neither 74S procapsids nor 14S particles were detected in the cel...

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Udgivet i:J Virol
Principais autores: Fiszman, Marc, Reynier, Max, Bucchini, Danielle, Girard, Marc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1972
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4345493/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.10.6.1143-1151.1972
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