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Thermosensitive Block of the Sabin Strain of Poliovirus Type I

The thermosensitive defect of the Sabin LSc2ab strain of poliovirus type I was studied. Transfer of infected KB cells from 36 to 38.5 C resulted in 30% inhibition of viral RNA replication but in 90% inhibition of formation of virions. Neither 74S procapsids nor 14S particles were detected in the cel...

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Detalhes bibliográficos
Main Authors: Fiszman, Marc, Reynier, Max, Bucchini, Danielle, Girard, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356595/
https://ncbi.nlm.nih.gov/pubmed/4345493
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