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Evidence that the endothelin A receptor can enhance IgE-dependent anaphylaxis in mice
Endothelin-1 has been implicated in inflammatory disorders including allergic responses. Here, we present evidence in mice that endothelin-1 may act via ET(A) to increase mast cell degranulation and thus exacerbate clinical features of anaphylaxis.
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565840/ https://ncbi.nlm.nih.gov/pubmed/21555149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.04.012 |
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