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Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice

BACKGROUND: Mast cells express receptors for complement anaphylatoxins C3a and C5a (i.e., C3aR and C5aR), and C3a and C5a are generated during various IgE-dependent immediate hypersensitivity reactions in vivo. However, it is not clear to what extent mast cell expression of C3aR or C5aR influences C...

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Detalhes bibliográficos
Main Authors: Schäfer, Beatrix, Piliponsky, Adrian M., Oka, Tatsuya, Song, Chang Ho, Gerard, Norma P., Gerard, Craig, Tsai, Mindy, Kalesnikoff, Janet, Galli, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597773/
https://ncbi.nlm.nih.gov/pubmed/22728083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.05.009
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