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A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations

Bromodeoxyuridine (BrdU) is widely used in immunology to detect cell division, and several mathematical models have been proposed to estimate proliferation and death rates of lymphocytes from BrdU labelling and de-labelling curves. One problem in interpreting BrdU data is explaining the de-labelling...

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Detalhes bibliográficos
Main Authors: Ganusov, Vitaly V., De Boer, Rob J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565791/
https://ncbi.nlm.nih.gov/pubmed/23034350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0617
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