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Structure-activity relationship study of novel anticancer aspirin-based compounds

We performed a structure-activity relationship (SAR) study of a novel aspirin (ASA) derivative, which shows strong anticancer activity in vitro and in vivo. A series of ASA-based benzyl esters (ABEs) were synthesized and their inhibitory activity against human colon (HT-29 and SW480) and pancreatic...

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Detalhes bibliográficos
Main Authors: JOSEPH, STANCY, NIE, TING, HUANG, LIQUN, ZHOU, HUI, ATMAKUR, KRISHNAIAH, GUPTA, RAMESH C., JOHNSON, FRANCIS, RIGAS, BASIL
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565583/
https://ncbi.nlm.nih.gov/pubmed/21805049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2011.534
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