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Synthesis and characterization of N, N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors

The sigma-1 receptor is a unique non-opioid, non-PCP binding site that has been implicated in many different pathophysiological conditions including psychosis, drug addiction, retinal degeneration and cancer. Based on the structure of fenpropimorph, a high affinity (K(i)= 0.005nM) (1) sigma-1 recept...

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Detaylı Bibliyografya
Asıl Yazarlar: Hajipour, Abdol R., Fontanilla, Dominique, Chu, Uyen B., Arbabian, Marty, Ruoho, Arnold E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565575/
https://ncbi.nlm.nih.gov/pubmed/20493718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.04.078
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