Surface-mediated release of a synthetic small-molecule modulator of bacterial quorum sensing: Gradual release enhances activity

We demonstrate an approach to the surface-mediated release of a synthetic N-acylated L-homoserine lactone (AHL) modulator of bacterial quorum sensing (QS). AHL released gradually from thin films of poly(lactide-co-glycolide) (PLG) is shown to activate QS in the model symbiont Vibrio fischeri at leve...

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Autori principali: Breitbach, Anthony S., Broderick, Adam H., Jewell, Christopher M., Gunasekaran, Suvai, Lin, Qi, Lynn, David M., Blackwell, Helen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565574/
https://ncbi.nlm.nih.gov/pubmed/20830354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02316g
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