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Surface-Mediated Release of a Small-Molecule Modulator of Bacterial Biofilm Formation: A Non-Bactericidal Approach to Inhibiting Biofilm Formation in Pseudomonas aeruginosa

We report an approach to preventing bacterial biofilm formation that is based on the surface-mediated release of 5,6-dimethyl-2-aminobenzimidazole (DMABI), a potent and non-bactericidal small-molecule inhibitor of bacterial biofilm growth. Our results demonstrate that DMABI can be encapsulated in th...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Broderick, Adam H., Breitbach, Anthony S., Frei, Reto, Blackwell, Helen E., Lynn, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248566/
https://ncbi.nlm.nih.gov/pubmed/23335593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201200334
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