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Mutation accumulation and fitness in mutator subpopulations of Escherichia coli
Bacterial populations in clinical and laboratory settings contain a significant proportion of mutants with elevated mutation rates (mutators). Mutators have a particular advantage when multiple beneficial mutations are needed for fitness, as in antibiotic resistance. Nevertheless, high mutation rate...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Royal Society
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565518/ https://ncbi.nlm.nih.gov/pubmed/23221876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2012.0961 |
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