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Antitumor Effects of Rapamycin in Pancreatic Cancer Cells by Inducing Apoptosis and Autophagy

Rapamycin (Rapa), an inhibitor of mammalian target of Rapamycin (mTOR), is an immunosuppressive agent that has anti-proliferative effects on some tumors. This study aims to investigate the effects of Rapa suppressing proliferation of pancreatic carcinoma PC-2 cells in vitro and its molecular mechani...

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Detalhes bibliográficos
Main Authors: Dai, Zhi-Jun, Gao, Jie, Ma, Xiao-Bin, Kang, Hua-Feng, Wang, Bao-Feng, Lu, Wang-Feng, Lin, Shuai, Wang, Xi-Jing, Wu, Wen-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565263/
https://ncbi.nlm.nih.gov/pubmed/23344033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14010273
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