Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo

BACKGROUND: Cyclooxygenase-2(COX-2) promotes carcinogenesis, tumor proliferation, angiogenesis, prevention of apoptosis, and immunosuppression. Meanwhile, COX-2 over-expression has been associated with tumor behavior and prognosis in several cancers. This study investigated the antitumor effects of...

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Detalhes bibliográficos
Main Authors: Dai, Zhi-Jun, Ma, Xiao-Bin, Kang, Hua-Feng, Gao, Jie, Min, Wei-Li, Guan, Hai-Tao, Diao, Yan, Lu, Wang-Feng, Wang, Xi-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558357/
https://ncbi.nlm.nih.gov/pubmed/23249419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-12-53
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