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Effects of histone acetylation and CpG methylation on the structure of nucleosomes

Nucleosomes are the fundamental packing units of the eukaryotic genome. A nucleosome core particle comprises an octameric histone core wrapped around by ~147 bp DNA. Histones and DNA are targets for covalent modifications mediated by various chromatin modification enzymes. These modifications play c...

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Autores principales: Lee, Ju Yeon, Lee, Tae-Hee
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565240/
https://ncbi.nlm.nih.gov/pubmed/22627143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.05.006
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