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Effects of histone acetylation and CpG methylation on the structure of nucleosomes
Nucleosomes are the fundamental packing units of the eukaryotic genome. A nucleosome core particle comprises an octameric histone core wrapped around by ~147 bp DNA. Histones and DNA are targets for covalent modifications mediated by various chromatin modification enzymes. These modifications play c...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565240/ https://ncbi.nlm.nih.gov/pubmed/22627143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.05.006 |
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