Defensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus

Human β defensin DEFB103 acts as both a stimulant and an attenuator of chemokine and cytokine responses: a dichotomy that is not entirely understood. Our predicted results using an in silico simulation model of dendritic cells and our observed results in human myeloid dendritic cells, show that DEFB...

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Autors principals: Harvey, Lauren E., Kohlgraf, Karl G., Mehalick, Leslie A., Raina, Monica, Recker, Erica N., Radhakrishnan, Saumya, Prasad, Samiksha Avinash, Vidva, Robinson, Progulske-Fox, Ann, Cavanaugh, Joseph E., Vali, Shireen, Brogden, Kim A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565171/
https://ncbi.nlm.nih.gov/pubmed/23390582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01232
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