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Microscopic mechanism of protein cryopreservation in an aqueous solution with trehalose
In order to investigate the cryoprotective mechanism of trehalose on proteins, we use molecular dynamics computer simulations to study the microscopic dynamics of water upon cooling in an aqueous solution of lysozyme and trehalose. We find that the presence of trehalose causes global retardation of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565168/ https://ncbi.nlm.nih.gov/pubmed/23390573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01218 |
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