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Genetically Engineered Excitable Cardiac Myofibroblasts Coupled to Cardiomyocytes Rescue Normal Propagation and Reduce Arrhythmia Complexity in Heterocellular Monolayers

RATIONALE AND OBJECTIVE: The use of genetic engineering of unexcitable cells to enable expression of gap junctions and inward rectifier potassium channels has suggested that cell therapies aimed at establishing electrical coupling of unexcitable donor cells to host cardiomyocytes may be arrhythmogen...

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Detalhes bibliográficos
Main Authors: Hou, Luqia, Hu, Bin, Jalife, José
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564921/
https://ncbi.nlm.nih.gov/pubmed/23393574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055400
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