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Electrotonic Myofibroblast-to-Myocyte Coupling Increases Propensity to Reentrant Arrhythmias in Two-Dimensional Cardiac Monolayers

In pathological conditions such as ischemic cardiomyopathy and heart failure, differentiation of fibroblasts into myofibroblasts may result in myocyte-fibroblast electrical coupling via gap junctions. We hypothesized that myofibroblast proliferation and increased heterocellular coupling significantl...

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Detalhes bibliográficos
Main Authors: Zlochiver, Sharon, Muñoz, Viviana, Vikstrom, Karen L., Taffet, Steven M., Berenfeld, Omer, Jalife, José
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567962/
https://ncbi.nlm.nih.gov/pubmed/18658226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.136473
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