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Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines

BACKGROUND: Obtaining a germ cell line is one of the most important steps in developing a transgenic or knockout mouse with a targeted mutated gene of interest. A common problem with this technology is that embryonic stem (ES) cells often lack, or are extremely inefficient at, germ line transmission...

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Detalhes bibliográficos
Main Authors: Kim, Young Mi, Lee, Ji-Yun, Xia, Lijun, Mulvihill, John J, Li, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564830/
https://ncbi.nlm.nih.gov/pubmed/23320952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-6-3
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