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Time line of redox events in aging postmitotic cells
The precise roles that oxidants play in lifespan and aging are still unknown. Here, we report the discovery that chronologically aging yeast cells undergo a sudden redox collapse, which affects over 80% of identified thiol-containing proteins. We present evidence that this redox collapse is not trig...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564446/ https://ncbi.nlm.nih.gov/pubmed/23390587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00306 |
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