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Time line of redox events in aging postmitotic cells

The precise roles that oxidants play in lifespan and aging are still unknown. Here, we report the discovery that chronologically aging yeast cells undergo a sudden redox collapse, which affects over 80% of identified thiol-containing proteins. We present evidence that this redox collapse is not trig...

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Detalhes bibliográficos
Main Authors: Brandes, Nicolas, Tienson, Heather, Lindemann, Antje, Vitvitsky, Victor, Reichmann, Dana, Banerjee, Ruma, Jakob, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564446/
https://ncbi.nlm.nih.gov/pubmed/23390587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00306
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