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Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage

The chemopreventive agent curcumin has anti-proliferative effects in many tumour types, but characterization of cell cycle arrest, particularly with physiologically relevant concentrations, is still incomplete. Following oral ingestion, the highest concentrations of curcumin are achievable in the gu...

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Detalhes bibliográficos
Main Authors: Blakemore, Louise M., Boes, Christoph, Cordell, Rebecca, Manson, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564441/
https://ncbi.nlm.nih.gov/pubmed/23125222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs345
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