Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival

The minor allele (G) of rs4939827, a SMAD7 (18q21) intronic variant, is associated with a lower risk of developing colorectal cancer (CRC) and poorer survival after diagnosis. Our objective was to evaluate the associations of this variant with different tumor phenotype and intratumoral molecular cha...

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Autors principals: Garcia-Albeniz, Xabier, Nan, Hongmei, Valeri, Linda, Morikawa, Teppei, Kuchiba, Aya, Phipps, Amanda I., Hutter, Carolyn M., Peters, Ulrike, Newcomb, Polly A., Fuchs, Charles S., Giovannucci, Edward L., Ogino, Shuji, Chan, Andrew T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564438/
https://ncbi.nlm.nih.gov/pubmed/23104301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs335
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