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S-Nitrosothiol-Modified Dendrimers as Nitric Oxide Delivery Vehicles

The synthesis and characterization of two generation-4 polyamidoamine (PAMAM) dendrimers with S-nitrosothiol exteriors are reported. The hyperbranched macromolecules were modified with either N-acetyl-D,L-penicillamine (NAP) or N-acetyl-L-cysteine (NACys) and analyzed via (1)H and (13)C-NMR, UV abso...

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Autors principals: Stasko, Nathan A., Fischer, Thomas H., Schoenfisch, Mark H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564213/
https://ncbi.nlm.nih.gov/pubmed/18247567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm7011746
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