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S-Nitrosothiol-Modified Nitric Oxide-Releasing Chitosan Oligosaccharides as Antibacterial Agents

S-nitrosothiol-modified chitosan oligosaccharides were synthesized by reaction with 2-iminothiolane hydrochloride and 3-acetamido-4,4-dimethylthietan-2-one, followed by the thiol nitrosation. The resulting nitric oxide (NO)-releasing chitosan oligosaccharides stored ~0.3 μmol NO/mg chitosan. Both th...

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Publicat a:Acta Biomater
Autors principals: Lu, Yuan, Shah, Anand, Hunter, Rebecca A., Soto, Robert J., Schoenfisch, Mark H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499378/
https://ncbi.nlm.nih.gov/pubmed/25449913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.10.028
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