Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia

Therapeutic hypothermia is of relevance to treatment of increased body temperature and brain injury, but drugs inducing selective, rapid, and safe cooling in humans are not available. Here, we show that injections of adenosine 5′-monophosphate (AMP), an endogenous nucleotide, promptly triggers hypot...

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Bibliographic Details
Main Authors: Muzzi, Mirko, Blasi, Francesco, Masi, Alessio, Coppi, Elisabetta, Traini, Chiara, Felici, Roberta, Pittelli, Maria, Cavone, Leonardo, Pugliese, Anna Maria, Moroni, Flavio, Chiarugi, Alberto
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564191/
https://ncbi.nlm.nih.gov/pubmed/23093068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.157
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