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Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia

Therapeutic hypothermia is of relevance to treatment of increased body temperature and brain injury, but drugs inducing selective, rapid, and safe cooling in humans are not available. Here, we show that injections of adenosine 5′-monophosphate (AMP), an endogenous nucleotide, promptly triggers hypot...

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Bibliografiske detaljer
Main Authors: Muzzi, Mirko, Blasi, Francesco, Masi, Alessio, Coppi, Elisabetta, Traini, Chiara, Felici, Roberta, Pittelli, Maria, Cavone, Leonardo, Pugliese, Anna Maria, Moroni, Flavio, Chiarugi, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564191/
https://ncbi.nlm.nih.gov/pubmed/23093068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.157
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