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Dopamine protects neurons against glutamate-induced excitotoxicity

Glutamate excitotoxicity is responsible for neuronal death in acute neurological disorders including stroke, trauma and neurodegenerative disease. Loss of calcium homeostasis is a key mediator of glutamate-induced cell death. The neurotransmitter dopamine (DA) is known to modulate calcium signalling...

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Detalhes bibliográficos
Main Authors: Vaarmann, A, Kovac, S, Holmström, K M, Gandhi, S, Abramov, A Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563982/
https://ncbi.nlm.nih.gov/pubmed/23303129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.194
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