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GM-CSF produced by non-hematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa,

GM-CSF is a growth factor that promotes the survival and activation of macrophages and granulocytes, and dendritic cell (DC) differentiation and survival in vitro. The mechanism by which exogenous GM-CSF ameliorates the severity of Crohn’s disease in humans and colitis in murine models has been cons...

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Autors principals: Egea, Laia, McAllister, Christopher S., Lakhdari, Omar, Minev, Ivelina, Shenouda, Steve, Kagnoff, Martin F.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563922/
https://ncbi.nlm.nih.gov/pubmed/23325885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202368
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